NAD+ and its function within the body
Nicotinamide adenine dinucleotide (NAD+) is a derivative of niacin (B3) and turns carbohydrates, fats, and amino acids into nutrients that fuel the body. Scientists investigating brain health and longevity have found that NAD+ is an essential coenzyme that promotes cellular regeneration and brain restoration. Studies have found replenishing cellular levels of NAD+ can repair DNA, protect brain cells from damage, reduce inflammation and turn on enzymes that help prevent aging. In addition to being central to managing metabolism. Optimizing cellular function is another benefit of NAD+, which is needed for every cell within our body. NAD is a coenzyme that is effective in elevating mood and minimizing feelings of depression and anxiety. In addition, it has been shown to replenish the brain’s neurotransmitters which decrease due to the constant state of activation of the nervous system and body.1 When NAD+ is low we can start to experience mental fogginess and anxiety among other symptoms.
The process of NAD+
NAD+ works by transferring electrons from one molecule to another within cells to carry out many reactions and processes. With its molecular counterpart, NADH, this vital molecule participates in various metabolic reactions that generate cells’ energy. Without sufficient NAD+ levels, cells wouldn’t be able to generate any energy to survive and carry out their functions. Another important function of NAD+ includes regulating our body’s sleep/wake cycle.2
Another class of enzymes that use NAD+ is called sirtuins. Sirtuin regulates the cellular processes including the aging and death of cells and their stress resistance. NAD+ supplementation may be helpful in antiaging intervention, providing hope to aging societies worldwide.3
By middle age, NAD+ levels have plummeted to half (see graph) that of youth. Many studies have shown that boosting NAD+ levels increase insulin sensitivity, reverses mitochondrial dysfunction, and extends lifespan.4
For more history on NAD+, click below
FAQs
What happens when NAD+ levels decrease?
Many studies show reduced NAD+ levels in conditions, such as obesity, and aging. Reductions in NAD+ levels can lead to problems with metabolism. Obesity can cause diabetes, high blood pressure, and other heart function decline; and can send damaging pressure waves to the brain that may lead to cognitive impairment. Brain fog and low energy are also a symptom of low NAD+ levels.
Why do people take NAD+?
People take NAD+ supplements for a variety of reasons, including enhancement in sports performance, a younger complexion and to fight age-related diseases.
How can someone increase their NAD+ levels?
Regular exercise boosts NAD+ levels as well as intermittent fasting. Also, certain foods increase NAD+ levels such as dairy, mushrooms, yeast, chicken, green vegetables, and whole grains. In addition, NAD+ supplementation comes in a variety of forms and is another option.
What is the best form of NAD+ for absorption?
There are several forms of NAD+; oral, sublingual tablets, powder, and an IV infusion. When ingested orally, absorption is reduced and less is provided to the body as it is processed through the digestive system. Sublingual tablets dissolve under the tongue and are absorbed by the digestive system, then go directly into the bloodstream. The best method for absorption and the highest potency is an IV infusion which goes directly into the bloodstream and bypasses the digestive system completely. Fort Wayne IV Lounge recommends an NAD+ infusion for better absorption and faster results.
NAD+ IV Infusion pricing
[1] nadmd.com/
[2] ncbi.nlm.nih.gov/pmc/articles/PMC6657305/